{
  "id": "c0f56741-21e8-5fc2-a8d9-1b151d16108a",
  "slug": "c3-2-d1-3-defence-against-disease-mutations",
  "title": "C3.2–D1.3 Defence Against Disease & Mutations",
  "course": "IB Biology",
  "level": "SL and HL",
  "syllabusRange": [
    "C3.2",
    "D1.3"
  ],
  "questionCount": 9,
  "page": "https://splycr.com/ib-biology/c3-2-d1-3-defence-against-disease-mutations",
  "data": "https://splycr.com/library/c3-2-d1-3-defence-against-disease-mutations.json",
  "play": "https://splycr.com/?set=c0f56741-21e8-5fc2-a8d9-1b151d16108a",
  "source": {
    "name": "Biology by Bradford",
    "href": "https://biologybybradford.com"
  },
  "questions": [
    {
      "number": 1,
      "question": "Which white blood cells produce specific antibodies?",
      "answer": "B-lymphocytes (B-cells)",
      "wrongOptions": [
        "Antibodies (Immunoglobulins)",
        "Germline mutation",
        "Somatic mutation"
      ]
    },
    {
      "number": 2,
      "question": "What are the proteins called that bind to specific antigens to neutralize them?",
      "answer": "Antibodies (Immunoglobulins)",
      "wrongOptions": [
        "B-lymphocytes (B-cells)",
        "Somatic mutation",
        "Memory cells"
      ]
    },
    {
      "number": 3,
      "question": "Which cells remain in the blood to provide long-term immunity after an infection?",
      "answer": "Memory cells",
      "wrongOptions": [
        "Germline mutation",
        "Gene therapy",
        "Somatic mutation"
      ]
    },
    {
      "number": 4,
      "question": "A gene editing tool that uses a guide RNA and the Cas9 enzyme to target and cut DNA?",
      "answer": "CRISPR-Cas9",
      "wrongOptions": [
        "Guide RNA",
        "Cas9",
        "Gene therapy"
      ]
    },
    {
      "number": 5,
      "question": "The specific RNA molecule that directs the Cas9 enzyme to a target DNA sequence?",
      "answer": "Guide RNA",
      "wrongOptions": [
        "Gene therapy",
        "Memory cells",
        "CRISPR-Cas9"
      ]
    },
    {
      "number": 6,
      "question": "The enzyme in the CRISPR system that acts as \"molecular scissors\" to cut DNA?",
      "answer": "Cas9",
      "wrongOptions": [
        "CRISPR-Cas9",
        "Guide RNA",
        "Memory cells"
      ]
    },
    {
      "number": 7,
      "question": "A medical treatment that involves inserting functional genes into a patient's cells to treat disease?",
      "answer": "Gene therapy",
      "wrongOptions": [
        "Germline mutation",
        "Memory cells",
        "Somatic mutation"
      ]
    },
    {
      "number": 8,
      "question": "A mutation occurring in body cells that is not passed on to offspring?",
      "answer": "Somatic mutation",
      "wrongOptions": [
        "Memory cells",
        "Gene therapy",
        "Germline mutation"
      ]
    },
    {
      "number": 9,
      "question": "A mutation occurring in gametes (eggs/sperm) that can be inherited by offspring?",
      "answer": "Germline mutation",
      "wrongOptions": [
        "Gene therapy",
        "Somatic mutation",
        "Memory cells"
      ]
    }
  ]
}