{
  "id": "e203107a-9da2-59d8-92fc-655eeea5db5e",
  "slug": "d1-3-mutations-and-gene-editing",
  "title": "D1.3 Mutations and Gene Editing",
  "course": "IB Biology",
  "level": "SL",
  "syllabusCode": "D1.3",
  "questionCount": 10,
  "page": "https://splycr.com/ib-biology/d1-3-mutations-and-gene-editing",
  "data": "https://splycr.com/library/d1-3-mutations-and-gene-editing.json",
  "play": "https://splycr.com/?set=e203107a-9da2-59d8-92fc-655eeea5db5e",
  "section": {
    "name": "Theme D: Continuity and change",
    "page": "https://splycr.com/ib-biology/continuity-and-change"
  },
  "source": {
    "name": "Biology by Bradford",
    "href": "https://biologybybradford.com"
  },
  "questions": [
    {
      "number": 1,
      "question": "General term for any change in the base sequence of DNA?",
      "answer": "Mutation",
      "wrongOptions": [
        "Deletion",
        "Insertion",
        "Mutagen"
      ]
    },
    {
      "number": 2,
      "question": "A mutation in a body cell, which is not passed on to offspring?",
      "answer": "Somatic mutation",
      "wrongOptions": [
        "Nonsense mutation",
        "Silent mutation",
        "Missense mutation"
      ]
    },
    {
      "number": 3,
      "question": "The replacement of one nucleotide with another in a DNA sequence?",
      "answer": "Substitution",
      "wrongOptions": [
        "Deletion",
        "Nonsense mutation",
        "Mutation"
      ]
    },
    {
      "number": 4,
      "question": "The addition of one or more nucleotides into a DNA sequence?",
      "answer": "Insertion",
      "wrongOptions": [
        "Mutation",
        "Deletion",
        "Mutagen"
      ]
    },
    {
      "number": 5,
      "question": "The removal of one or more nucleotides from a DNA sequence?",
      "answer": "Deletion",
      "wrongOptions": [
        "Insertion",
        "Mutation",
        "Mutagen"
      ]
    },
    {
      "number": 6,
      "question": "A mutation that shifts the reading frame of every subsequent codon (caused by insertion/deletion)?",
      "answer": "Frameshift mutation",
      "wrongOptions": [
        "Silent mutation",
        "Nonsense mutation",
        "Missense mutation"
      ]
    },
    {
      "number": 7,
      "question": "An agent that causes mutations, such as radiation or specific chemicals?",
      "answer": "Mutagen",
      "wrongOptions": [
        "Mutation",
        "Insertion",
        "Deletion"
      ]
    },
    {
      "number": 8,
      "question": "A mutation that does not change the amino acid sequence of the resulting protein?",
      "answer": "Silent mutation",
      "wrongOptions": [
        "Missense mutation",
        "Nonsense mutation",
        "Somatic mutation"
      ]
    },
    {
      "number": 9,
      "question": "A mutation that results in a single amino acid being changed in the protein?",
      "answer": "Missense mutation",
      "wrongOptions": [
        "Silent mutation",
        "Somatic mutation",
        "Nonsense mutation"
      ]
    },
    {
      "number": 10,
      "question": "A mutation that creates a premature stop codon, shortening the protein?",
      "answer": "Nonsense mutation",
      "wrongOptions": [
        "Silent mutation",
        "Somatic mutation",
        "Missense mutation"
      ]
    }
  ]
}
